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Methods PubMed, Medline, Embase, the Cochrane Center Register of Controlled Trials for Studies, and Clinicaltrials.gov were searched from the inception to March 2024

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Participants received weekly doses of one of the following: CagriSema 2.4/2.4 milligrams (mg), meaning 2.4 mg of cagrilintide and 2.4 mg of semaglutide CagriSema 1 / 1 mg, or 1 mg of cagrilintide and 1 mg of semaglutide 2.4 mg of semaglutide 1 mg of semaglutide 2.4 mg of cagrilintide a placebo

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